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Don’t fight Maculopapular cutaneous mastocytosis alone.
Find your community on the free RareGuru App.Maculopapular cutaneous mastocytosis (also known as urticaria pigmentosa) is a common form of cutaneous mastocytosis characterized by brown patches or freckles on the skin that result from an abnormal collection of mast cells. The skin may be very itchy and rubbing may lead to hive-like bumps or fluid-filled blisters. The condition is most common in children, but adults can also be affected. Treatment may include antihistamines, topical steroids, and/or phototherapy. Over time, the mastocytosis in younger patients usually becomes less itchy and the skin patches tend to improve. In adults, systemic mastocytosis may develop.
Source: GARD Last updated on 05-01-20
Maculopapular cutaneous mastocytosis occurs when there are too many inflammatory cells (called mast cells) in the skin. The underlying reason for this excess of mast cells is not fully understood. While most cases appear to be random (occur sporadically for no apparent reason), familial cases have been reported. These familial cases are thought to be inherited in an autosomal dominant manner and may be caused by mutations in the KIT gene.
Last updated on 05-01-20
The prognosis for children with maculopapular cutaneous mastocytosis is good. Up to 50% of cases improve and 30% of cases resolve completely by adolescence.
Last updated on 05-01-20
Maculopapular cutaneous mastocytosis is generally not serious and many cases do not require treatment. For those cases that do, oral antihistamines, topical steroids, and a photochemotherapy called PUVA may be used. These treatments are aimed at reducing the symptoms of the condition and making patients more comfortable.
Last updated on 05-01-20
The National Institute of Allergy and Infectious Diseases (NIAID) supports scientists developing better ways to diagnose, treat, and prevent the many infectious, immunologic, and allergic diseases that afflict people worldwide. Click on the link to view information on this topic.
Last updated on 04-27-20
The Mastocytosis Society provides information about mast cell diseases, including Maculopapular cutaneous mastocytosis.
Last updated on 04-27-20
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