Collagenous colitis

How might collagenous colitis be treated?

Treatment for collagenous colitis varies depending on the symptoms and severity in each person. The main goals of treatment are to decrease the number of bowel movements per day (typically to less than 3, with no watery bowel movements) and to improve quality of life. In some cases the condition may resolve on its own (spontaneous remission), although most people continue to have ongoing or occasional diarrhea. The response to different therapies differs from person to person, so more than one therapy may need to be tried (alone or in combination with others).

Treatment options that have been tried with varying success include:

  • Dietary changes such as a reduced-fat diet and/or eliminating foods that contain caffeine and lactose.
  • Avoiding or discontinuing medications that some people have reported triggered the disease (such as NSAIDS and proton pump inhibitors).
  • Antidiarrheal medications such as loperamide.
  • Corticosteroids such as budesonide.
  • Anti-TNF therapies such as infliximab and adalimumab.
  • Surgery to remove all or part of the colon in severe cases that to not respond to other treatment options.

Last updated on 05-01-20

Name: Crohn's & Colitis Foundation of America 733 Third Avenue, Suite 510
New York, NY, 10017, United States
Toll Free: 1–800–932–2423 Email: Url: Speak with a specialist by telephone at 888-MY-GUT-PAIN (888-694-8872)

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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