Acanthosis nigricans

How can acanthosis nigricans (AN) be treated?

There is no specific treatment for AN. Treatments are used mostly to improve cosmetic appearance and include topical retinoids, vitamin D creams (such as calcipotriol), dermabrasion and laser therapy. Oral retinoid pills have also been used to treat AN, but are not used for most patients because of the multiple side effects and development problems associated with the treatment. Treatment may also focus on trying to correct the underlying disease that causes AN to develop. Often correcting the underlying disease improves the skin symptoms. Some steps that can be taken depending on the underlying disease include: correcting hyperinsulinaemia through diet and medication, losing weight with obesity-associated AN, removing or treating a tumor, or stopping medications that cause AN.

Last updated on 05-01-20

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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