Twenty-nail dystrophy

What causes twenty-nail dystrophy?

The cause of twenty-nail dystrophy is unknown. In some cases, twenty-nail dystrophy has been diagnosed in people who also have another condition such as alopecia areata, or psoriasis. There are a few reported cases where several members of the same family have been affected by this condition, which suggests that there may be a genetic cause.

Last updated on 05-01-20

Can twenty-nail dystrophy cause hair loss?

There is a recognized association between hair loss and twenty-nail dystrophy, but it is not known if one condition causes the other. Individuals with twenty-nail dystrophy often also have hair loss, though the extent of hair loss varies from mild to severe. In severe cases of hair loss, the individual may have a condition called alopecia areata.

Last updated on 05-01-20

Can twenty-nail dystrophy affect adults?

Although the symptoms of twenty-nail dystrophy usually begin in childhood, adults can also be affected by this condition. One article in the medical literature describes a woman who first showed symptoms of this condition at age 21. Another article describes an individual who was 63 when he first developed symptoms in his fingernails, but his toenails were not affected. He was diagnosed with tachyonychia, and twenty-nail dystrophy is thought to be a type of tachyonychia.

Last updated on 05-01-20


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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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