Autoimmune encephalitis

How is autoimmune encephalitis diagnosed?

Diagnosis of autoimmune encephalitis can be made when all three of the following criteria have been met:

1. Subacute onset (rapid progression of less than 3 months) of working memory deficits (short-term memory loss), altered mental status, or psychiatric symptoms

2. At least one of the following:

• New focal CNS findings
• Seizures not explained by a previously known seizure disorder
• CSF pleocytosis (white blood cell count of more than five cells per mm3)
• MRI features suggestive of encephalitis

3. Reasonable exclusion of alternative causes

A team of leading autoimmune encephalitis researchers have established diagnostic criteria for these conditions. View the full position paper, entitled A Clinical Approach to Diagnosis of Autoimmune Encephalitis.

For more on diagnosis, visit the following link to the International Autoimmune Encephalitis Society Web site:

Last updated on 05-01-20

In-Depth Information

International Autoimmune Encephalitis Society

The International Autoimmune Encephalitis Society lists up-to-date research articles, videos, podcasts, and slide shows with detailed information on autoimmune encephalitis.

Last updated on 04-27-20

Where To Start

Autoimmune Encephalitis Alliance

The Autoimmune Encephalitis Alliance has a list of frequently asked questions (FAQ) about autoimmune encephalitis.

Last updated on 04-27-20

Name: Encephalitis Society 32 Castlegate Malton, North Yorkshire YO17 7DT
United Kingdom
Phone: +44 (0)1653 699599 Email: Url: Social media: Twitter: @encephalitis Facebook: /encephalitissociety
Name: American Autoimmune Related Diseases Association (AARDA) 22100 Gratiot Avenue
Eastpointe, MI, 48021, United States
Phone: 586-776-3900 Toll Free: 800-598-4668 Fax : 586-776-3903 Email: Url:
Name: Autoimmune Encephalitis Alliance 920 Urban Avenue
Durham, NC, 27701,
Email: Url:
Name: International Autoimmune Encephalitis Society United States Phone: 352-527-2470 Email: Url:
Name: Hashimoto’s Encephalopathy SREAT Alliance HESA Email: Url:

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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