Atrophoderma of Pierini and Pasini is thought to possibly represent a late stage of morphea a type of localized scleroderma. Signs and symptoms of atrophoderma of Pierini and Pasini include multiple oval, darkened (hyperpigmented) plaques in which tissue under the skin breaks down so that there is a depression (dent) within the skin. Some findings suggest that atrophoderma of Pierini and Pasini may be associated with _B burgdorferi, _a bacteria that causes Lyme disease, __ in some cases.
Source: GARD Last updated on 05-01-20
No single treatment of atrophoderma of Pierini and Pasini is consistently effective. Therapies that have been tried include topical corticosteroids, antibiotics, and antimalarials. There have been reports of symptom improvement with the use of hydroxychloroquine, potassium aminobenzoate, and improvement following surgical care using a Q-switched alexandrite laser, however these findings have not been confirmed by larger studies. If a person with atrophoderma of Pierini and Pasini tests positive for B burgdorferi antibody, standard Lyme disease therapy is often recommended. Click here to visit the Center for Disease Control and Prevention's Lyme Disease Information Resource pages to learn more about Lyme disease therapy.
Last updated on 05-01-20
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