Astroblastoma

Whether a particular astroblastoma is technically non-cancerous or cancerous (malignant) depends on the histological findings (examination of the affected tissue under a microscopic) in each tumor. Malignant astroblastomas are generally characterized by higher cellularity (the number of its constituent cells) and proliferation; necrosis (death of cells or tissues); and vascular proliferation (growth of blood vessels within the tumor).

Astroblastoma is a rare glial tumor usually located in the cerebral hemisphere of the brain. It can occur in individuals of any age, but occurs predominantly in children and young adults. Signs and symptoms depend on the location and size of the tumor but most commonly include headaches and seizures. Because these tumors are rare, there is little known regarding their behavior and how they should be managed. Gross total resection (complete removal) of the tumor is recommended and is associated with a good prognosis for low- grade tumors. Adjuvant therapy, including radiation and/or chemotherapy, is recommended for high- grade and recurrent cases (although its effectiveness is controversial).

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