Reticulohistiocytoma

What causes reticulohistiocytoma?

While it is known that reticulohistiocytoma (RH) develop due to a rapid production of immune cells (histiocytes) in the skin or soft tissues, the cause of this process is not currently known.

Last updated on 05-01-20

How is reticulohistiocytoma diagnosed?

The diagnosis of reticulohistiocytoma (RH) is made based on clinical presentation, histology, and immunohistochemistry profile. RH occur in isolation and are typically described as small, yellow to reddish-born nodules. The lesions usually are slightly elevated from the surrounding skin. Detailed information on histology of reticulohistiocytoma is available through DermNet NZ, an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated.

There are several differential diagnoses for RH. It is important to distinguish RH from Rosai-Dorfman disease, juvenile xanthogranuloma, a variety of granulomatous conditions, and some malignant neoplasms, including histiocytic sarcoma, melanoma, and epithelioid sarcoma.

Reticulohistiocytoma should also be distinguished from multicentric reticulohistiocytosis.

Last updated on 05-01-20

What is the long-term outlook for reticulohistiocytoma?

The long-term outlook (prognosis) for Reticulohistiocytoma (RH) is good. RH is thought to represent a benign skin lesion. RH tends to spontaneously resolve over a period of months to years and affected individuals remain healthy. Recurrence of RH is rare.

Last updated on 05-01-20

How might reticulohistiocytoma be treated?

Reticulohistiocytoma (RH) typically resolve spontaneously over a period of months to years; however, surgical excision usually results in a cure.

Last updated on 05-01-20

Name: Histiocytosis Association 332 North Broadway
Pitman, NJ, 08071 , United States
Phone: +1-856-589-6606 Toll Free: 1-800-548-2758 (from US and Canada) Fax : +1-856-589-6614 Email: info@histio.org Url: https://www.histio.org/
Name: Histiocytosis Association of Canada 41 Milverton Close Waterdown, ON
L8B 0A9
Canada
Email: info@histio.ca Url: https://histiocytosis.ca/
Reticulohistiocytoma pathology DermNetNZ. February, 2015; Reference Link

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