Pustulosis palmaris et plantaris

What causes pustulosis palmaris et plantaris?

The cause of pustulosis palmaris et plantaris (PPP) is not fully understood, though many theories have been proposed. Some have suggested PPP may be a disorder of the sweat glands. Environmental factors are believed to play a part as well. For instance, there is a strong association between smoking and PPP. Other environmental factors that may contribute to PPP include stress, infections (especially tonsillitis and sinusitis), and certain medications. Some have also suggested an association with allergies to certain metals. Although most cases occur in people with no family history of the condition, more than one family member can be affected. This suggests that genetic factors may contribute to the development of the condition in some cases.

Last updated on 05-01-20

How might pustulosis palmaris et plantaris be treated?

Although there is no cure for pustulosis palmaris et plantaris, various measures may be useful to manage symptoms. General suggestions include smoking cessation and emollients (non-cosmetic moisturizers) to soften dry skin and prevent cracking. Topical corticosteroids (steroids), an oral retinoid such as acitretin, and photochemotherapy (ultraviolet radiation treatment) are often first-line treatments. Other methods that may be utilized when initial treatment options fail include a combination of oral retinoid and photochemotherapy or immunosuppressive therapy with medications such as cyclosporine.

Last updated on 05-01-20

Name: National Psoriasis Foundation NPF 6600 SW 92nd Ave., Suite 300
Portland, OR, 97223-7195, United States
Phone: +1-503-244-7404 Toll Free: 1-800-723-9166 Fax : +1-503-245-0626 Email: getinfo@psoriasis.org Url: https://www.psoriasis.org/

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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