Primary sclerosing cholangitis

Does worsening pain indicate the progession of primary sclerosing cholangitis?

The natural course of primary sclerosing cholangitis (PSC) is chronic (long lasting) and progressive (worsens over time). Stomach pain can be an early symptom of PSC (e.g., associated with infection or gallstones), a symptom of progressed disease (e.g. cirrhosis, portal hypertension, cholestasis), or associated with a co-occurring autoimmune disorder (e.g., ulcerative colitis) or cancer (e.g., cholangiocarcinoma). In addition to stomach pain, other signs and symptoms that could signal advanced disease or cancer include persistent jaundice and weight loss. We strongly encourage you to speak with your healthcare provider regarding the cause of your increased pain.

Last updated on 05-01-20

How often should screenings and tests be done to detect the progression and secondary complications of primary sclerosing cholangitis?

The signs and symptoms experienced by a person with primary sclerosing cholangitis (PSC) can help guide decisions regarding testing. The benefits of routine screening of people with PSC for early detection of cholangiocarcinoma is debated, however it has been suggested that people with PSC undergo annual screening for cholangiocarcinoma with either an ultrasound or MRI with MRCP, plus measurement of a serum CA 19-9. Once again, we recommend that you speak with your healthcare provider to learn more about your testing and screening options.

Last updated on 05-01-20

Where To Start

Primary sclerosing cholangitis

The National Cancer Institute provides detailed information on extrahepatic bile duct cancer. Click on the link to view the information page.

Last updated on 04-27-20

Name: PSC Partners Seeking a Cure 6900 E. Belleview Avenue, Suite 202
Greenwood Village, CO, 80111-1627,
Phone: 303-771-5227 Email: contactus@pscpartners.org Url: http://www.pscpartners.org/
Name: American Autoimmune Related Diseases Association (AARDA) 22100 Gratiot Avenue
Eastpointe, MI, 48021, United States
Phone: 586-776-3900 Toll Free: 800-598-4668 Fax : 586-776-3903 Email: aarda@aarda.org Url: https://www.aarda.org/

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