Primary melanoma of the central nervous system

What causes primary melanoma of the central nervous system?

Although the exact cause of this condition is unknown, researchers have identified somatic mutations in the the GNAQ gene in 7 of 19 patients (37 percent) with primary malignant melanocytic tumors of the central nervous system. Somatic mutations are not inherited but occur during a person's lifetime. This mutation makes the Gnaq protein constantly active. The same mutation has been identified in approximately half of patients with intraocular melanoma.

Last updated on 05-01-20

Name: American Brain Tumor Association 8550 W. Bryn Mawr Ave, Ste 550
Chicago, IL, 60631, United States
Phone: +1-773-577-8750 Toll Free: 1-800-886-2282 Fax : +1-773-577-8738 Email: info@abta.org Url: https://www.abta.org/
Name: National Brain Tumor Society 55 Chapel St., Suite 200
Newton, MA, 02458, United States
Phone: +1-617-924-9997 Fax : +1-617-924 -9998 Email: http://braintumor.org/our-mission/contact-us/ Url: http://braintumor.org/

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