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Papular mucinosis is a rare skin disorder characterized by deposits of mucin in the skin. The terms "papular mucinosis" and "lichen myxoedematosus" are generally used interchangeably to describe the occurrence of this condition as a localized and less severe form, while the term scleromyxoedema refers to a generalized, more severe form. Signs and symptoms of the condition include the presence of small, firm, waxy papules on the skin that are confined to a few sites on the body. Affected individuals are typically otherwise healthy. The cause of the condition is unknown, but it is commonly associated with monoclonal gammopathy. It has also been reported in association with bone marrow cancers as well HIV infection, hepatitis C, exposure to toxic oil and contaminated L-tryptophan. Localized papular mucinosis typically does not require therapy, but topical corticosteroids and oral isotretinoin may help to reduce hardening of the skin.
Source: GARD Last updated on 05-01-20
You can find relevant articles on this condition through PubMed, a searchable database of biomedical journal articles. Although not all of the articles are available for free online, most articles listed in PubMed have a summary available. To obtain the full article, contact a medical/university library or your local library for interlibrary loan. You can also order articles online through the publisher’s Web site. Using "papular mucinosis" or "lichen myxedematosus" as your search term should help you locate articles. Use the Advanced and/or Limits search features to narrow your search results. Click here to view a search: http://www.ncbi.nlm.nih.gov/PubMed
The National Library of Medicine (NLM) Web site has a page for locating libraries in your area that can provide direct access to these journals (print or online). The Web page also describes how you can get these articles through interlibrary loan and Loansome Doc (an NLM document-ordering service). You can access this page at the following link http://nnlm.gov/members/. You can also contact the NLM toll-free at 888-346-3656 to locate libraries in your area.
The U.S. National Institutes of Health, through the National Library of Medicine, developed ClinicalTrials.gov to provide patients, family members, and members of the public with current information on clinical research studies. Although there may not be trials listed for this condition at a particular point in time, the site is updated regularly and can be checked often for updates. To search for trials on this condition, click on the link above and use "papular mucinosis" or "lichen myxedematosus" as your search term.
Last updated on 05-01-20
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