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An ostium secundum atrial septal defect is a type of congenital heart defect called an atrial septal defect (ASD). An ASD is a hole in the wall (septum) between the two upper chambers of the heart (the atria). ASDs can be classified by location. An ostium secundum ASD is a hole in the center of the atrial septum.
Normally, the right side of the heart pumps oxygen-poor blood to the lungs, while the left side pumps oxygen-rich blood to the body. An ASD allows blood from both sides to mix, causing the heart to work less efficiently.
A small hole may not cause any symptoms or problems. A larger hole can eventually cause symptoms such as shortness of breath, respiratory infections, fainting, irregular heart rhythms or fatigue after mild activity. Larger ASDs can also ultimately lead to pulmonary artery hypertension, right ventricular hypertrophy (enlargement); SVT, or heart failure.
Most cases of ASD are not inherited and occur by chance. Some cases appear to have autosomal dominant inheritance.
Source: GARD Last updated on 05-01-20
Most atrial septal defects (ASDs) occur sporadically (by chance), though familial transmission has also been reported. Some cases appear to have autosomal dominant inheritance. Some genetic syndromes with skeletal abnormalities associated with ASD also have autosomal dominant inheritance.
It is not possible to predict whether the child of a person with an ASD, or another congenital heart defect, will be affected. Because of the possibility that it can be familial, the family and medical history should be carefully evaluated by a cardiologist or a genetics professional. These specialists can address questions and concerns and assess recurrence risks.
Additionally, women with congenital heart disease (or whose partner has congenital heart disease) should be offered fetal echocardiography in the 19th to 22nd week of pregnancy to evaluate the fetal heart.
Last updated on 05-01-20
Atrial septal defect (ASD) is the most common repaired or unrepaired lesion in pregnant women with congenital heart disease. Once an atrial septal defect (ASD) is closed and there is no residual hole, the risk of maternal cardiac complications is very low. The only circumstance in which pregnancy is not advised in women with ASDs (whether repaired or not) is the presence of severe pulmonary arterial hypertension. No significantly increased risk of fetal complications in patients with repaired ASDs was reported in a large, multinational study published in 2011.
In order to make informed pregnancy decisions, women with congenital heart disease should have a preconception (pre-pregnancy) evaluation by a cardiologist with expertise in pregnancy and congenital heart disease. Women with congenital heart disease should also be offered fetal echocardiography in the 19th to 22nd week of pregnancy to evaluate the fetal heart.
Last updated on 05-01-20
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