Nonseminomatous germ cell tumor

Does having a parent with nonseminomatous germ cell tumor increase one’s chances of developing the cancer?

The cause of cancer in general can be broadly described as multifactorial, with genetic, environmental, medical, and lifestyle factors interacting to produce a given cancer. Knowledge of the role of genetics in certain cancers has greatly improved over time, but much remains to be learned. We were unable to find information in the medical literature that suggests that having a first degree relative, such as a parent, with nonseminomatous germ cell tumor is a risk factor for this cancer. At this time, recognized risk factors for nonseminomatous germ cell tumor include being 20-years-old or older, being male, and having Klinefelter syndrome. Click here to learn more about Klinefelter syndrome. Click here to read more about cancer genetics in general, including a list of the general signs of hereditary cancer.

Last updated on 05-01-20

Are there any clinical trials investigating the role of genetics in nonseminomatous germ cell tumor?

While we are not aware of a clinical trial currently investigating the role of genetics in nonseminomatous germ cell tumor, you may be interested in learning more about the Cancer Genetics Network. The Cancer Genetics Network is a national network of centers specializing in the study of inherited predisposition to cancer.

You may also find it helpful to periodically search for new trials at ClinicalTrials.gov. The National Institutes of Health, through the National Library of Medicine, developed ClinicalTrials.gov to provide patients, family members, and members of the public with current information on clinical research studies. To search for a study, use "genetic AND germ cell tumor" as your search term.

You can also contact the Patient Recruitment and Public Liaison (PRPL) Office at the National Institutes of Health (NIH). We recommend calling the toll-free number listed below to speak with a specialist, who can help you determine if you are eligible for any clinical trials.

Patient Recruitment and Public Liaison Office (PRPL)
NIH Clinical Center
Bethesda, Maryland 20892-2655
Toll-free: 800-411-1222
Fax: 301-480-9793
Email: prpl@mail.cc.nih.gov
Web site: http://clinicalcenter.nih.gov/

ClinicalTrials.gov provides ahelpful guide for information about participating in a clinical trial. Resources for travel and lodging assistance are listed on the National Center for Advancing Translational Sciences Office of Rare Diseases Research (NCATS-ORDR) website, part of the National Institutes of Health (NIH).

Lastly, you may be interested in learning more about the Cancer Genome Anatomy Project (CGAP). The Project seeks to determine the gene expression profiles of normal, precancer, and cancer cells, leading eventually to improved detection, diagnosis, and treatment for the patient.

Last updated on 05-01-20

Where To Start

Extra gonadal germ cell tumor info page - testicular resource

The Testicular Cancer Resource Center has an information page on extragonadal germ cell cancer. Click on the link above to view the information page.

Last updated on 04-27-20

Name: American Cancer Society 250 Williams Street NW
Atlanta, GA, 30329, United States
Toll Free: 1-800-227-2345 Url: https://www.cancer.org
Name: Cancer Hope Network 2 North Road, Suite A
Chester, NJ, 07930, United States
Phone: +1-908-879-4039 Toll Free: 1-877-467-3638 (1-877-HOPENET) Fax : +1-908-879-6518 Email: info@cancerhopenetwork.org/ Url: https://www.cancerhopenetwork.org/
Name: Rare Cancer Alliance 1649 North Pacana Way
Green Valley, AZ, 85614, United States
Phone: 520-625-5495 Url: http://www.rare-cancer.org
Name: The Rarer Cancers Foundation Unit 7B Evelyn Court
Grinstead Road London, SE8 5AD
United Kingdom
Phone: 0208 692 2910 Toll Free: 0800 334 5551 (in the UK) Email: helpline@rarercancers.org.uk Url: http://www.rarercancers.org.uk
Name: CancerCare 275 Seventh Ave, Floor 22
New York, NY, 10001 , United States
Toll Free: 800-813-HOPE Fax : 212-712-8495 Email: info@cancercare.org Url: http://www.cancercare.org/

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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