Non 24 hour sleep wake disorder

What is non 24 hours sleep wake disorder?

Non 24 hour sleep wake disorder refers to a steady pattern of one- to two- hour delays in sleep onset and wake times in people with normal living conditions. This occurs because the period of the person's sleep-wake cycle is longer than 24 hours. The condition most commonly affects people who are blind, due to an impaired sense of light-dark cycles. Non 24 hour sleep wake disorder can also affect sighted people. The cause of the disorder in these cases is incompletely understood, but studies suggest melatonin levels play a role.

Last updated on 05-01-20

Is non 24 hour sleep wake disorder genetic in sighted people with this disorder?

Non 24 hour sleep wake disorder is not known to be inherited, and we were unable to find case reports of this condition clustering in a family. There have been a few studies to see if changes in the MTNR1A and MTNR1B genes affect disease risk. Findings were inconclusive, however one person with non 24 hour sleep wake disorder was found to carry a gene change in both of these genes.

Last updated on 05-01-20

Name: American Sleep Association 110 W. Ninth Street, Suite 826
Wilmington, DE, 19801 , United States
Fax : 940-234-3357 Email: Url:
Name: Circadian Sleep Disorders Network Email: Url:

Connect with other users with Non 24 hour sleep wake disorder on the RareGuru app

Do you have information about a disease, disorder, or syndrome? Want to suggest a symptom?
Please send suggestions to RareGuru!

The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

People Using the App

Join the RareGuru Community

To connect, share, empower and heal today.

People Using the App