Multifocal motor neuropathy

What causes multifocal motor neuropathy?

The exact underlying cause of multifocal motor neuropathy (MMN) is poorly understood. It is considered an immune-mediated disorder (due to an abnormal immune system response), both because IVIG therapy improves symptoms, and many patients have anti-GM1 antibodies. Research to further understand the cause of MMN is underway.

Last updated on 05-01-20

Is multifocal motor neuropathy inherited?

We are not aware of any evidence that multifocal motor neuropathy (MMN) is inherited or of any reports of familial cases (occurring in more than one person in a family). Furthermore, to our knowledge, no specific genes known to be associated with MMN have been identified.

Last updated on 05-01-20

How might multifocal motor neuropathy be treated?

Multifocal motor neuropathy (MMN) is considered treatable with intravenous immune globulin (IVIG). Early treatment shortly after symptoms begin is recommended. Most people have a fairly rapid improvement in weakness with IVIG, but the improvement generally does not last beyond a few months. Maintenance IVIG infusions are usually needed every two to six weeks. For those with severe disease whose symptoms don't respond to IVIG (or for those who become resistant), treatment options are limited. Several reports have suggested that cyclophosphamide may be partially effective.

Last updated on 05-01-20

Where To Start

GBS/CIDP Foundation International

The GBS/CIDP Foundation International provides information about this condition. The GBS|CIDP Foundation International is a global non-profit organization supporting individuals and families affected by Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy (CIDP), and related syndromes through a commitment to support, education, research, and advocacy.

Last updated on 04-27-20

Neuropathy Action Foundation

The Neuropathy Action Foundation (NAF) provides an online information about Multifocal motor neuropathy. The NAF is dedicated to ensuring neuropathy patients obtain resources, information and tools to access individualized treatment to improve their quality of life.

Last updated on 04-27-20

Name: GBS/CIDP Foundation International 375 East Elm Street, Suite 101
Conshohocken, PA, 19428, United States
Phone: +1-610-667-0131 Toll Free: 1-866-224-3301 (from North America) Fax : +1-610-667-7036 Email: Url:
Name: The Foundation for Peripheral Neuropathy 485 Half Day Road Suite 350
Buffalo Grove, IL, 60089,
Phone: +1-877-883-9942 Fax : +1-847-883-9960 Email: Url:
Name: Neuropathy Action Foundation 1950 Old Tustin Avenue
Santa Ana, CA, 92705,
Toll Free: (877) 512-7262 Email: Url:

Connect with other users with Multifocal motor neuropathy on the RareGuru app

Do you have information about a disease, disorder, or syndrome? Want to suggest a symptom?
Please send suggestions to RareGuru!

The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

People Using the App

Join the RareGuru Community

To connect, share, empower and heal today.

People Using the App