Membranoproliferative glomerulonephritis
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The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.
Orpha Number: 54370
Definition
Membranoproliferative glomerulonephritis (MPGN) is a chronic progressive kidney disorder characterized by glomerular capillary wall structural changes and mesangial cell proliferation leading to nephrotic syndrome, hypocomplementemia, hypertension, proteinuria and end-stage kidney disease. MPGN can be due to either idiopathic (type 1, 2 and 3 MPGN; see these terms) or secondary (associated with infectious and immune complex diseases) causes.
Visit the Orphanet disease page for more resources.
Source: GARD Last updated on 05-01-20
Symptoms
Symptoms and their Known Frequencies
30%-79% of people have these symptoms.
Click on a symptom to see definitions for associated terms.
5%-29% of people have these symptoms.
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| Thigh hypertrophy |
| Hypoalbuminemia |
| Abnormality of the skin |
| Acute kidney injury |
| Stage 5 chronic kidney disease |
1%-4% of people have these symptoms.
Click on a symptom to see definitions for associated terms.
| Shortening of all metacarpals |
| Metaphyseal cupping of metacarpals |
| Abnormal thrombosis |
| Drusen |
| Myocardial infarction |
An unknown % of people have these symptoms.
Click on a symptom to see definitions for associated terms.
King of Prussia, PA, 19406, Phone: 1-866-NephCure (637-4287) Email: info@nephcure.org Url: https://nephcure.org/
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