Don’t fight Membranoproliferative glomerulonephritis alone.
Find your community on the free RareGuru App.The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.
Orpha Number: 54370
Definition
Membranoproliferative glomerulonephritis (MPGN) is a chronic progressive kidney disorder characterized by glomerular capillary wall structural changes and mesangial cell proliferation leading to nephrotic syndrome, hypocomplementemia, hypertension, proteinuria and end-stage kidney disease. MPGN can be due to either idiopathic (type 1, 2 and 3 MPGN; see these terms) or secondary (associated with infectious and immune complex diseases) causes.
Visit the Orphanet disease page for more resources.
Source: GARD Last updated on 05-01-20
30%-79% of people have these symptoms.
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5%-29% of people have these symptoms.
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Thigh hypertrophy |
Hypoalbuminemia |
Abnormality of the skin |
Acute kidney injury |
Stage 5 chronic kidney disease |
1%-4% of people have these symptoms.
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Shortening of all metacarpals |
Metaphyseal cupping of metacarpals |
Abnormal thrombosis |
Drusen |
Myocardial infarction |
An unknown % of people have these symptoms.
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