Logopenic progressive aphasia

What is the typical life expectancy for people with logopenic progressive aphasia?

Little is known regarding the overall life expectancy of individuals with logopenic progressive aphasia. This dementia is associated with Alzheimer’s disease in the majority of cases. Life expectancy for people with Alzheimer’s disease has been estimated to be between 3 to 10 years. However, due to the many variables that influence life expectancy, making individualized life-expectancy predictions can be very difficult.

Last updated on 05-01-20

What is the prognosis for people with logopenic progressive aphasia?

Typically during the first few years following disease onset, signs and symptoms primarily involve speech and language problems. Pronounced behavioral problems are not as common in logopenic progressive aphasia, as in other forms of primary progressive aphasia. Caregiver experience of changes in behavioral symptoms and everyday skills has been demonstrated to be similar to that of Alzheimer’s disease.

Last updated on 05-01-20

How might logopenic progressive aphasia be treated?

Although no medications or interventions have demonstrated long-term stabilization of logopenic progressive aphasia (LPA), different treatment methods have shown promising short-term benefits. Studies utilizing language therapy and behavioral interventions have shown encouraging results. Neuromodulation through methodologies such as Transcranial Direct Current Stimulation (tDCS) and transcranial magnetic stimulation (rTMS) have additionally been identified as a promising therapies to potentially use in combination with behavioral treatment and language therapy.

As the most common underlying pathology of LPA is Alzheimer's disease (AD) pathology, limited research has been completed on interventions shown to reduce the rate of decline in cognitive symptoms in AD. So far cholinesterase inhibitors and memantine, medications used in Alzheimer’s disease, have not been proven effective in treating logopenic progressive aphasia. Case studies involving steriod use and Omentum Transposition Therapy have reported improvement; however, the results have not been replicated in other cases and as with other treatment options, long-term studies are lacking.

The National Aphasia Association provides further information on the medical management of primary progressive aphasias at the following link:

http://live-naa.pantheon.io/wp-content/uploads/2014/12/Managing-PPA.pdf

Last updated on 05-01-20

Where To Start

National Aphasia Association

The National Aphasia Association provides information on primary progressive aphasia and Logopenic progressive aphasia

Last updated on 04-27-20

Name: National Aphasia Association P.O. Box 87
Scarsdale, NY, 10583, United States
Toll Free: 800-922-4622 Email: naa@aphasia.org Url: http://www.aphasia.org
Name: Aphasia Hope Foundation 750 Woodlands Pkwy
Ridgeland, MS, 39157, United States
Phone: (913)-484-8302 Email: jstradinger.2007@comcast.net Url: http://aphasiahope.wpengine.com/
Name: Frontotemporal Lobar Degeneration Association (FTLDA) 21019 U.S. Hwy. 281 Suite 830-27
San Antonio, TX, 78258, United States
Phone: 210-824-9510 Email: oxford@ftlda.org Url: http://www.ftlda.org/

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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