Light chain deposition disease

Is light chain deposition disease considered a cancer?

Technically, light chain deposition disease (LCDD) is not considered a cancer. However, it shares some characteristics with cancer, and can be associated with certain types of cancer.

LCDD is a clonal plasma cell proliferative disorder in which fragments of light chains (parts of antibodies made by plasma cells) multiply uncontrollably and deposit in tissues of the body. In cancer, specific types of entire cells multiply, and may spread into surrounding tissues. Like cancer, the process occurring in LCDD is difficult to stop or slow down, and can ultimately lead to organ damage and failure.

LCDD is associated with multiple myeloma in many cases. Multiple myeloma is a cancer due to malignant plasma cells, which are the same type of cells involved in LCDD. A person may first have LCDD and then develop multiple myeloma, or they may both be found to be present when a person is first diagnosed. LCDD can also be associated with lymphoma.

Last updated on 05-01-20

Where To Start

Light chain deposition disease

The International Multiple Myeloma Foundation offers information on light chain deposition disease on their Web site. Click on the link above to view the information page.

Last updated on 04-27-20

Name: American Cancer Society 250 Williams Street NW
Atlanta, GA, 30329, United States
Toll Free: 1-800-227-2345 Url:
Name: Leukemia and Lymphoma Society 3 International Drive, Suite 200
Rye Brook, NY, 10573, United States
Phone: 1-(888) 557-7177 (general) Toll Free: 1-(800) 955-4572 (patients and families) Email: Url:
Name: International Myeloma Foundation 12650 Riverside Drive, Suite 206
North Hollywood, CA, 91607-3421, United States
Phone: 818-487-7455 Toll Free: 800-452-2873 Email: Url:

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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