Lichen planopilaris

What causes lichen planopilaris?

The cause of lichen planus is unknown but it is thought to be an autoimmune disorder in which white blood cells attack and destroy skin cells expressing unknown antigens. Triggering factors may include pharmacologic agents, contact sensitizers or infectious agents.

Last updated on 05-01-20

How might lichen planopilaris be treated?

There is not yet a cure for lichen planopilaris. Treatment depends on how much of the scalp is affected and how quickly the condition progresses. A high or moderate potency steroid cream is often effective in treating lichen planopilaris. If this is not effective, steroid injections (into skin lesions), or systemic corticosteroids (taken by mouth) may be considered. Hydroxychloroquine (Plaquenil), retinoids (Accutane), oral cyclosporine, methotrexate, mycophenolate mofetil, rituximab, and pioglitazone have also been used to treat lichen planopilaris with some success, although information on these treatments is limited. Unfortunately even with successful treatment, lichen planopilaris can return.

Last updated on 05-01-20

Name: Cicatricial Alopecia Research Foundation (C.A.R.F.) 1586 Sumneytown Pike PO Box 1322
Kulpsville, PA, 19443, United States
Phone: +1-267-613-9811 Email: Url:
Name: National Lichen Sclerosus Support Group P.O. Box 5830 Lyme Regis
Dorset DT7 3ZU
United Kingdom
Phone: 07765 947599 Url:
Name: American Autoimmune Related Diseases Association (AARDA) 22100 Gratiot Avenue
Eastpointe, MI, 48021, United States
Phone: 586-776-3900 Toll Free: 800-598-4668 Fax : 586-776-3903 Email: Url:

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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