Insulin autoimmune syndrome

What causes insulin autoimmune syndrome?

Insulin autoimmune syndrome occurs suddenly as antibodies are produced that attack the insulin which the body is producing naturally. Because a person affected by this condition is producing antibodies to attack a naturally occurring substance, the condition is classified as a type of autoimmune syndrome. This means that the immune system, which is responsible for protecting the body from disease, is instead attacking the body itself.

Exactly why these antibodies against insulin are suddenly produced can vary from person to person. In some cases, insulin autoimmune syndrome occurs in a person with another autoimmune disease, which can indicate that the immune system in the body is not behaving correctly. Additionally, a certain class of medications called sulphydryl compounds have been shown to sometimes cause insulin autoimmune syndrome. Some of these medications are used to treat other autoimmune conditions. Recently, a compound called alpha-lipoic acid has been associated with an increased risk of developing insulin autoimmune syndrome. This compound is sometimes used for dieting purposes.

Last updated on 05-01-20

How is insulin autoimmune syndrome diagnosed?

Insulin autoimmune syndrome may be diagnosed by measuring blood sugar levels, insulin levels, and ruling out other conditions that can cause low blood sugar. Certain tests may also be used to test for the presence of antibodies that attack insulin. All of these tests can be completed using blood from a blood test.

Last updated on 05-01-20

What is the long-term outlook for people affected with insulin autoimmune syndrome?

Most people affected by insulin autoimmune syndrome find that their symptoms go away after a few months. It may be important to stop taking any medications that may be triggering the condition. Some people, however, do experience recurrent attacks where they experience low blood sugar levels. With proper treatment, any recurrent episodes can likely be controlled.

Last updated on 05-01-20

What is the treatment for insulin autoimmune syndrome?

The treatment of insulin autoimmune syndrome is similar to treatments for other conditions that cause low blood sugar. This includes eating smaller meals more frequently in order to maintain a more consistent blood sugar level and continuous monitoring of blood sugar. Additional treatment options can include treatment with steroids and a procedure called plasmaphoresis which removes the blood from the body, separates the insulin antibodies in the blood stream, and replaces the blood without the antibodies. Any damage to the pancreas may also require treatment.

Last updated on 05-01-20

Name: American Autoimmune Related Diseases Association (AARDA) 22100 Gratiot Avenue
Eastpointe, MI, 48021, United States
Phone: 586-776-3900 Toll Free: 800-598-4668 Fax : 586-776-3903 Email: Url:

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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