Idiopathic thrombocytopenic purpura

Can idiopathic thrombocytopenic purpura be inherited?

The cause of idiopathic thrombocytopenic purpura (ITP) is unknown. It is not thought to be genetic because it is rare for multiple people in the same family to develop this disease. Only a few cases of familial ITP have been documented, including an affected woman and 3 of her 4 children, identical twins with chronic ITP, and a mother with chronic ITP who had a child with purpura. The child's purpura resolved on its own within 3 weeks while the mother remained thrombocytopenic.

Last updated on 05-01-20

Is Evans syndrome inherited?

While Evans syndrome is not thought to be inherited in most cases and rarely occurs in more than one person in a family, there are a few cases in the medical literature describing "familial Evans syndrome." The majority of familial cases involve siblings that are found to have Evans syndrome. Some of these cases were additionally associated with other symptoms, such as heart defects as well as other disorders that are known to be inherited, such as hereditary spastic paraplegia.

If there is a family history of Evans syndrome, we would recommend consulting with a genetics professional to discuss risks for family members.

Last updated on 05-01-20

Can Evans syndrome cause infertility?

A review of available literature does not yield any information or case reports regarding Evans syndrome and infertility. Furthermore, infertility is not mentioned as being a sign or symptom of Evans syndrome in various resources.

Evans syndrome appears to be rare in pregnancy with only a few published cases. Because some of the medications used to treat Evan's syndrome may be harmful to a developing baby, treatment options in pregnancy can be limited. However, women with Evans syndrome can have successful pregnancies.

Last updated on 05-01-20

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Phone: +1-703-935-8845 Toll Free: 1-877-466-2568 (877-4NO-CLOT) Email: Url:
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Name: Vascular Cures 274 Redwood Shores Parkway, #717
Redwood City, CA, 94065, United States
Phone: +1-650-368-6022 Email: Url:
Name: ITP Foundation 30 Old Kings Hwy South, Suite 275
Darien, CT, 06820 , United States
Phone: 203-655-6954 Fax : 203-548-9182 Email: Url:
Name: American Autoimmune Related Diseases Association (AARDA) 22100 Gratiot Avenue
Eastpointe, MI, 48021, United States
Phone: 586-776-3900 Toll Free: 800-598-4668 Fax : 586-776-3903 Email: Url:

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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