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Alezzandrini syndrome is a very rare syndrome characterized by retinitis pigmentosa (breakdown and loss of cells in the retina—which is the light sensitive tissue that lines the back of the eye), whitish patches in the skin (vitiligo) and whitening of eyebrow and eyelashes (poliosis) all on the same side of the face. It is very similar to Vogt-Koyanagi-Harada syndrome. Other reported signs and symptoms may include vision loss and retinal detachment, a patch of white hair in the scalp, a café-u-lait spot on the neck, and hearing loss, again, all on the same side as the affected eye. The cause is unknown, but may be related to viral infections or autoimmune processes. Medical care includes eye exams, hearing tests and treatment for the vitiligo skin lesions.
Source: GARD Last updated on 05-01-20
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