Hemoglobin Zurich

What is hemoglobin Zurich?

Hemoglobin (Hb) Zurich is an inherited blood disorder. People with Hb Zurich have an abnormal form of Hb, a red blood cell (RBC) protein that binds to oxygen in the lungs. This abnormal Hb more readily binds to carbon monoxide (producing carboxyhemoglobin or COHb). Normally the level of COHb is less than 1-2% in adults. People with Hb Zurich tend to have COHb levels above 3%. The health effects of Hb Zurich tend to be mild compared to other inherited blood cell disorders. Symptoms usually develop only when the body is stressed due to an infection or fever or when exposed to certain drugs. Symptoms develop as a result of the premature breakdown of RBC (hemolytic anemia). Click here to visit MedlinePlus.gov and view an illustration of hemoglobin.

Last updated on 05-01-20

How might hemoglobin Zurich be treated?

The most important aspect of management for hemoglobin (Hb) Zurich is to avoid agents that might trigger hemolytic anemia. Mild hemolytic anemia may not need treatment, as long as the condition doesn't worsen. Treatments for severe hemolytic anemia include blood transfusions, medicines, and plasmapheresis. Click here to visit the National Heart Lung and Blood Institute to learn more about treatment.

Last updated on 05-01-20


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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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