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Don’t fight Growth hormone deficiency alone.
Find your community on the free RareGuru App.Growth hormone deficiency (GHD) is characterized by abnormally short height due to lack (or shortage) of growth hormone. It can be congenital (present at birth) or acquired. Most cases are identified in children. Although it is uncommon, growth hormone deficiency may also be diagnosed in adults. Too little growth hormone can cause short stature in children, and changes in muscle mass, cholesterol levels, and bone strength in adults. Most of the time, no single clear cause can be identified but several genetic causes of GHD have been described, such as mutations in the to POU1F1/Pit1 , PROP1 GHRH and GH1 genes. In adolescents, puberty may be delayed or absent. Treatment involves growth hormone injections.
Source: GARD Last updated on 05-01-20
The investigators involved in the Utah Growth study estimated the prevalence of pediatric growth hormone deficiency in the United States as at least 1 case per 3480 children. While this study was published in 1994, we were unable to identify more recent domestic data. CLICK HERE to read the abstract of this report published in The Journal of Pediatrics.
Regarding adult growth hormone deficiency, the authors of the Medscape Reference article on this topic write, " An estimated 6,000 adults are diagnosed with GH deficiency every year in the United States. Adult GH deficiency has been estimated to affect 1 in 100,000 people annually."
Last updated on 05-01-20
The Endocrine Society has developed a Transitions of Care toolkit to help care teams ease the transition from a pediatric doctor to a new adult doctor.
Last updated on 04-27-20
The Pediatric Endocrine Society provides an online fact sheet entitled "Growth Hormone Deficiency: A Guide for Families."
Last updated on 04-27-20
Note, these links are external searches against the National Laboratory of Medicine's drug database. You may need to adjust the search if there are no results found.
| Drug Name | Generic Name |
|---|---|
| Macrelin | macimorelin acetate |
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