Gastrointestinal Stromal Tumors

How might gastrointestinal stromal tumors be treated?

For patients with primary, localized gastrointestinal stromal tumors (GIST), surgery with complete excision is often the first line of treatment. However, surgery may not be as successful in the treatment of recurrent and metastatic GIST.

The TKI imatinib mesylate (imatinib) may be used as the first treatment option for tumors which cannot be removed completely by surgery (unresectable), cancerous GIST that has spread (metastatic), or recurrent GIST. TKI sunitinib malate (sunitinab) is generally given to people if treatment with imatinib has not been successful. KIT and PDGFRA genetic testing may help predicting tumor responses to kinase inhibitors.

Last updated on 05-01-20

Other Links

The Life Raft Group

The The Life Raft Group Newsroom Web page provides up-to-date information about the latest news related to GIST. Click on the link above to view this resource.

Last updated on 04-27-20

Where To Start

GIST - Web sites and resources

The Global GIST Network is a directory of resources available to people with Gastrointestinal Stromal Tumors and their families. This directory serves to help people throughout the world find local resources and support.

Last updated on 04-27-20


The American Cancer Society (ACS) has developed a detailed guide on GIST. To access this guide, visit the ACS link.

Last updated on 04-27-20

Name: The Life Raft Group 40 Galesi Drive, Ste. 19
Wayne, NJ, 07470 , United States
Phone: 973-837-9092 Fax : 973-837-9095 Url:
Name: GIST Cancer Research Fund GCRF 3905 N.E. 167th Street
North Miami Beach, FL, 33160, United States
Phone: 305-944-4590 Email: Url:

Note, these links are external searches against the National Laboratory of Medicine's drug database. You may need to adjust the search if there are no results found.

Drug Name Generic Name
Ayvakit avapritinib

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