Episodic angioedema with eosinophilia

What causes episodic angioedema with eosinophilia?

The cause of episodic angioedema with eosinophilia (EAE) is not well understood. Experts suspect that certain proteins in the immune system called interleukins may play a role. Specifically, interleukin 5 (IL-5) levels are elevated during episodes. Studies have lead to the belief that these proteins play a role in the inflammatory process involved in EAE.

Last updated on 05-01-20

What is the long-term outlook for episodic angioedema with eosinophilia?

Generally, episodic angioedema with eosinophilia (EAE) is considered to be a benign condition with a self limiting course. Typically, other organs are not involved and over time, episodes may resolve on their own. In some instances, people with EAE can develop symptoms in other organs, such as cardiac disease. Symptoms may also progress to other types of non episodic hypereosinophilic syndrome.

Last updated on 05-01-20

How might episodic angioedema with eosinophilia be treated?

Treatment may not be needed for episodic angioedema with eosinophilia (EAE), since symptoms usually resolve on their own. When treatment is initiated, steroids are usually the first choice. Certain medications used to treat cancer, including Imatinib (Gleevac) have also been successfully used in treating EAE.

Last updated on 05-01-20

Name: American Partnership For Eosinophilic Disorders PO Box 29545
Atlanta, GA, 30359, United States
Phone: 713-493-7749 Email: mail@apfed.org Url: http://www.apfed.org
Name: International Eosinophil Society 555 East Wells Street, Suite 1100
Milwaukee, WI, 53202, United States
Phone: 414-276-6445 Email: info@eosinophil-society.org/ Url: http://www.eosinophil-society.org/

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