Eosinophilic granulomatosis with polyangiitis

Can skin rashes and spots mean that eosinophilic granulomatosis with polyangiitis has relapsed?

Skin involvement is one of the most common features of the vasculitic phase of eosinophilic granulomatosis with polyangiitis. Half to two-thirds of affected people have skin lesions. They usually appear as tender subcutaneous nodules on the arm (particularly the elbows), hands, and legs. Skin lesions can also appear as a red rash or hemorrhagic lesions.

Relapses involving vasculitis occur in about 30 to 50 percent of affected people. However, the chance to have a severe relapse can be minimized by prompt reporting of any new symptoms. With prompt and proper treatment, it is possible to achieve remission again after a relapse. People who have been in remission and are having any symptoms that may be related to eosinophilic granulomatosis with polyangiitis should speak with their health care provider to be evaluated and treated if necessary.

Last updated on 05-01-20

What is the long-term outlook for people with eosinophilic granulomatosis with polyangiitis?

The prognosis may still depend on the severity of the illness in each person and the specific organ systems that are affected. In general, the prognosis has improved significantly since the use of corticoids and selected use of immunosuppressant agents for people with more severe disease. Although eosinophilic granulomatosis with polyangiitis can be progressive and serious, many affected people do very well.

If treatment is started early and the disease is carefully monitored, organ damage may be reduced. Even people with very severe cases can get well (remission) when treated promptly and followed closely. However, it is possible for eosinophilic granulomatosis with polyangiitis to recur. People with asthma or nasal allergies often have worsening of these symptoms, independent of vasculitis. Relapses involving vasculitis occur in about 30% to 50% of affected people. The chance to have a severe relapse can be minimized by prompt reporting of any new symptoms. Relapses are treated the same way as when the disease started for the first time, and it is possible to achieve remission again after a relapse.

Most deaths in affected people are due to complications from the vasculitic phase of eosinophilic granulomatosis with polyangiitis and are most commonly due to heart failure and/or heart attack; kidney failure; cerebral bleeding; gastrointestinal bleeding; and acute, or severe asthma (status asthmaticus).

Last updated on 05-01-20

Where To Start

Churg Strauss syndrome

Last updated on 04-27-20

Name: Vasculitis Foundation P.O. Box 28660
Kansas City, MO, 64188, United States
Phone: +1-816-436-8211 Toll Free: 1-800-277-9474 Fax : +1-816-656-3838 Email: https://www.vasculitisfoundation.org/contact-us-2/ Url: https://www.vasculitisfoundation.org/
Name: American Partnership For Eosinophilic Disorders PO Box 29545
Atlanta, GA, 30359, United States
Phone: 713-493-7749 Email: mail@apfed.org Url: http://www.apfed.org
Name: Churg Strauss Syndrome Association PO Box 671
Southampton, MA, 01073-0671 , United States
Phone: 413-862-3636 Email: support@CSSAssociation.org Url: http://www.cssassociation.org
Name: American Autoimmune Related Diseases Association (AARDA) 22100 Gratiot Avenue
Eastpointe, MI, 48021, United States
Phone: 586-776-3900 Toll Free: 800-598-4668 Fax : 586-776-3903 Email: aarda@aarda.org Url: https://www.aarda.org/

Note, these links are external searches against the National Laboratory of Medicine's drug database. You may need to adjust the search if there are no results found.

Drug Name Generic Name
Nucala mepolizumab

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