Encephalitis lethargica

Are there any documented cases of meningioma in survivors of encephalitis lethargica?

After an extensive review of the medical literature, we were not able to find a report of meningioma occurring in a survivor of encephalitis lethargica (EL). As the majority of cases occurred between 1917 and 1928, there may be a lack of data in the medical literature reporting symptoms of survivors of EL. If you are interested in searching for journal articles on encephalitis lethargica, you can use the online PubMed database. We have included a sample search on our resource page for encephalitis lethargica.

Last updated on 05-01-20

What is encephalitis lethargica?

Encephalitis lethargica (EL) is a disease characterized by high fever, headache, double vision, delayed physical and mental response, extreme tiredness (lethargy), and sometimes coma. Patients may also experience abnormal eye movements, upper body weakness, muscle pain, tremors, neck rigidity, and behavioral changes including psychosis. A worldwide epidemic of EL occurred from 1917 to 1928 with more than one million reported cases. Although occasional cases are reported with similar symptoms, EL epidemics have not recurred. The cause of this condition is unknown, but a viral origin is suspected. Treatment depends on a person's symptoms. Levodopa and other antiparkinson drugs may be effective in alleviating some symptoms.

Last updated on 05-01-20


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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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