Dysfibrinogenemia

Can dysfibrinogenemia go away as a person ages?

Congenital dysfibrinogenemia, the inherited form caused by mutations in specific genes, is present from birth and throughout life, even though a person may not have symptoms.

Acquired dysfibrinogenemia may be due to a number of conditions, including liver disease (such as cirrhosis, hepatitis, or liver tumors); renal carcinoma (kidney cancer); isotretinoin therapy; and biliary obstruction. In these cases, the abnormal fibrinogen may disappear with treatment of the underlying condition, or may disappear spontaneously (on its own).

Last updated on 05-01-20

How many people have dysfibrinogenemia?

Congenital dysfibrinogenemia is considered rare, but the true incidence is unknown since many forms don't cause signs or symptoms. In the literature, only 200-300 families have been reported.

Approximately 50% of patients with severe liver disease have bleeding tendencies secondary to abnormal fibrinogen (acquired dysfibrinogenemia).

Last updated on 05-01-20

Name: National Blood Clot Alliance 8321 Old Courthouse Road Suite 255
Vienna, VA, 22182, United States
Phone: +1-703-935-8845 Toll Free: 1-877-466-2568 (877-4NO-CLOT) Email: info@stoptheclot.org Url: https://www.stoptheclot.org/
Name: Vascular Cures 274 Redwood Shores Parkway, #717
Redwood City, CA, 94065, United States
Phone: +1-650-368-6022 Email: info@vascularcures.org Url: https://vascularcures.org/
Name: Clot Connect UNC Hemophilia and Thrombosis Center 6340 Quadrangle Drive, Suite 50
Chapel Hill, NC, 27517, United States
Email: http://www.clotconnect.org/about-clot-connect/contact-u Url: http://www.clotconnect.org/

Connect with other users with Dysfibrinogenemia on the RareGuru app

Do you have information about a disease, disorder, or syndrome? Want to suggest a symptom?
Please send suggestions to RareGuru!

The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

People Using the App

Join the RareGuru Community

To connect, share, empower and heal today.

People Using the App