Dieulafoy lesion

What causes Dieulafoy lesion?

Dieulafoy lesions may not cause symptoms until the lining of the stomach or intestine wears away, exposing the artery. The cause of Dieulafoy lesions is not well-understood. Some believe the lesions are congenital (present at birth), while others believe they occur later in life. In some cases, Dieulafoy lesions have been associated with prior stomach surgery. Possible associations between Dieulafoy lesions and alcohol intake and Dieulafoy lesions and the use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDS), and warfarin have been suggested.

Last updated on 05-01-20

How might a Dieulafoy lesion be diagnosed?

Dieulafoy lesions present a diagnostic challenge. The lesions are rare, often quite small in size, and may not bleed regularly. The heavy bleeding that may accompany the lesion and the small size of the lesion can make it hard to see on endoscopy. Methods of diagnosing a Dieulafoy lesion include endoscopy and angiography (the use of X-rays in combination with contrast dye). Abdominal CT scans may also be used.

Last updated on 05-01-20

How might a Dieulafoy lesion be treated?

Endoscopic techniques may be used to treat Dieulafoy lesions. These techniques may include the use of electrical current, heat, or argon gas to cause the blood to clot; injection of medications such as epinephrine; or the placement of bands or clips to close off the blood vessels. Angiography can also be used to treat the abnormal blood vessels (embolization). In some cases, surgery, either alone or in combination with endoscopic techniques, may be indicated.

Last updated on 05-01-20

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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