Diabetic mastopathy

What causes diabetic mastopathy?

The cause of diabetic mastopathy is unknown. Theories include an autoimmune reaction, genetic factors such as human leukocyte antigen (HLA) type, association with insulin therapy, and association with hyperglycemia.

Last updated on 05-01-20

How is diabetic mastopathy diagnosed?

The diagnosis of diabetic mastopathy should be considered in patients with long-standing insulin-dependent diabetes and a firm, mobile breast mass. Initial imaging studies may include mammography and ultrasound. While these methods can help to further differentiate the mass, they cannot provide a specific diagnosis of diabetic mastopathy with confident exclusion of malignancy. A core biopsy (utilizing a needle to remove a small cylinder of tissue) is often performed for a definitive diagnosis.

Last updated on 05-01-20

Does diabetic mastopathy increase a person's risk for developing breast cancer?

No. Research shows that diabetic mastopathy does not increase a person's risk for developing breast cancer. The small number of reported cases which describe malignancy in patients with diabetic mastopathy are believed to be due to coincidence. At this time, there is no pathologic literature linking diabetic mastopathy with malignancy.

Last updated on 05-01-20

Who should I talk to if I am concerned I may have breast cancer?

If you are concerned that you may have breast cancer we recommend that you speak with your health care provider.

Last updated on 05-01-20

Is pain in the breast a symptom of breast cancer?

Early breast cancer usually does not cause pain. Still, a person should see his/her health care provider about breast pain or any other symptom that does not go away. Most often, these symptoms are not due to cancer. Other health problems may also cause them. Any person with these symptoms should tell their doctor so that problems can be diagnosed and treated as early as possible.

Last updated on 05-01-20

Can diabetic mastopathy recur?

Yes. Diabetic mastopathy can recur. In patients with recurrence, the recurrence tends to be in the same location involving more breast tissue than previously seen.

Last updated on 05-01-20

How is diabetic mastopathy treated?

Typically, no treatment is necessary for diabetic mastopathy. Individuals with this condition should be advised about the condition and how to self examine the breasts to detect any changes in size and number of breast lumps. Patients should be routinely followed up with MRI or ultrasound and core biopsy if the lesions become clinically or radiologically suspicious. Lesions can be surgically removed for cosmetic reasons or if malignancy cannot be excluded.

Last updated on 05-01-20

Selected Full-Text Journal Articles

Diabetic Mastopathy - article

Ely RA, Tse G, Simpson JF, Clarfeld R, Page D. Diabetic Mastopathy: Clinicopathologic Review. Anatomic Pathology. 2000; 113:541-545.

Last updated on 04-27-20

Name: American Diabetes Association 2451 Crystal Drive Suite 900
Arlington, VA, 22202, United States
Toll Free: 1–800–DIABETES (342–2383) Fax : 703–549–6995 Email: AskADA@diabetes.org Url: http://www.diabetes.org
Name: Canadian Diabetes Association 1400-522 University AVE Toronto ON M5G 2R5
Toll Free: 800-226-8464 Email: info@diabetes.ca Url: http://www.diabetes.ca/
Name: Diabetes New Zealand Freepost DNZ PO Box 54
New Zealand
Toll Free: 0800 DIABETES (0800 342 238) Fax : 03 434 5281 Email: info@diabetes.org.nz Url: http://www.diabetes.org.nz/
Name: International Diabetes Federation (IDF) 166 Chaussee de la Hulpe B-1170 Brussels, Belgium
Phone: +32-2-5385511 Fax : +32-2-5385114 Email: info@idf.org Url: http://www.idf.org/

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The RareGuru disease database is regularly updated using data generously provided by GARD, the United States Genetic and Rare Disease Information Center.

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