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Don’t fight Cushing's syndrome alone.
Find your community on the free RareGuru App.Cushing's syndrome is an endocrine disorder caused by prolonged exposure of the body's tissues to high levels of cortisol (a hormone produced by the adrenal gland). It most commonly affects adults between age 20 and 50 years. Signs and symptoms of Cushing's syndrome include upper body obesity, fatigue, muscle weakness, high blood pressure, backache, high blood sugar, easy bruising and bluish-red stretch marks on the skin. Affected women may also experience irregular menstrual periods and increased growth of body and facial hair. This condition may be caused by a variety of factors including long-term use of corticosteroid medications, tumors in the pituitary gland or adrenal adenomas.Treatment depends on the underlying cause, but may include decreasing the dosage of corticosteroids or surgery to remove tumors.
Source: GARD Last updated on 05-01-20
The signs and symptoms of Cushing's syndrome may include:
Women with Cushing's syndrome may also experience increased growth of facial and body hair, and menstrual periods may become irregular or cease. Men may have decreased fertility, diminished sexual desire, and/or erectile dysfunction.
Last updated on 05-01-20
Cushing's syndrome is caused by long-term exposure of the body's tissues to cortisol, a hormone that is naturally produced by the adrenal gland. Exposure to too much cortisol can result from long-term use of corticosteriod medications used to treat inflammatory illnesses. Pituitary adenomas (benign tumors of the pituitary gland) or tumors of the adrenal gland may also cause cortisol imbalances.
Last updated on 05-01-20
Most cases of Cushing's syndrome are not inherited. However, Cushing's syndrome rarely occurs in inherited conditions characterized by the development of tumors of one or more endocrine gland. These conditions may include:
Last updated on 05-01-20
The Endocrine Society Clinical Practice Guideline for Cushing's syndrome was developed by the Endocrine Society, a global network of endocrinologists working as physicians, researchers, clinicians, scientists, and educators. The guidelines provide evidence-based recommendations for clinical care and practice.
Last updated on 04-27-20
The Cushing's Support and Research Foundation provides information and support for people with Cushing syndrome. Click on Cushing's Support and Research Foundation to view information on Cushing's.
Last updated on 04-27-20
Note, these links are external searches against the National Laboratory of Medicine's drug database. You may need to adjust the search if there are no results found.
| Drug Name | Generic Name |
|---|---|
| Signifor | pasireotide |
| Isturisa | osilodrostat |
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