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Collecting duct carcinoma (CDC) is a rare and aggressive form of kidney cancer that begins in the collecting duct of the kidney. Many people with CDC have no signs or symptoms until the cancer is at an advanced stage. Symptoms may include flank pain, unexplained weight loss, or blood in the urine. Although it can affect people of all ages, CDC tends to occur in younger patients. The exact cause of CDC is unknown. It usually occurs in people with no family history of the condition. Treatment options for CDC may include surgery and/or chemotherapy.
Source: GARD Last updated on 05-01-20
Treatment of collecting duct carcinoma (CDC) may include surgery to remove the kidney. Chemotherapy may also be given. The authors of a 2013 review article mentioned that gemcitabine and cisplatin should be considered the standard of care for chemotherapy treatment of metastatic CDC. This treatment regimen is similar to what is given for transitional cell carcinoma, also known as urothelial carcinoma. Immunotherapy was not shown to be effective in treating CDC. There are a few reports of promising results from targeted therapy such as sunitinib or sorafenib. Studies are underway to learn more about these treatment options.
Last updated on 05-01-20
The Kidney Cancer Association offers additional information on Collecting duct carcinoma. Please click on the link to access this resource.
Last updated on 04-27-20
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