Don’t fight Charcot-Marie-Tooth disease type 4C alone.Find your community on the free RareGuru App.
Charcot-Marie-Tooth disease is a group of disorders that affect the peripheral nerves, the nerves running from outside the brain and spine. Defects in many different genes cause different forms of this disease. Common symptoms may include foot drop, foot deformity, loss of lower leg muscle, numbness in the foot or leg, “slapping" gait (feet hit the floor hard when walking), and weakness of the hips, legs, or feet. There is currently no cure for Charcot-Marie-Tooth disease, but physical therapy, occupational therapy, braces and other orthopedic devices, pain medication, and orthopedic surgery can help manage and improve symptoms.
There are over 40 types of Charcot-Marie-Tooth disease. You can search for more information on a particular type of Charcot-Marie-Tooth disease from the GARD Home page. Enter the name of the condition in the GARD search box, and then select the type from the drop down menu.
Source: GARD Last updated on 05-01-20
An unknown % of people have these symptoms.
Click on a symptom to see definitions for associated terms.
|Abnormal cranial nerve morphology|
|Decreased motor nerve conduction velocity|
|Calcification of falx cerebri|
|Delayed eruption of permanent teeth|
|Increased serum pyruvate|
|Generalized bone demineralization|
|Absent pubic hair|
|Abnormal pupillary light reflex|
|Autosomal recessive inheritance|
|Basal lamina onion bulb formation|
|Decreased number of large peripheral myelinated nerve fibers|
|Distal muscle weakness|
|Distal sensory impairment|
|Peripheral axonal degeneration|
|Prolonged brainstem auditory evoked potentials|
|Segmental peripheral demyelination|
|Upper limb muscle weakness|
Do you have information about a disease, disorder, or syndrome? Want to suggest a symptom?
Please send suggestions to RareGuru!