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Don’t fight Catecholaminergic polymorphic ventricular tachycardia alone.
Find your community on the free RareGuru App.Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder that causes an abnormally fast and irregular heart rhythm in response to physical activity or emotional stress. Signs and symptoms include light- headedness, dizziness, and fainting. Symptoms most often develop between 7 to 9 years of age. If untreated CPVT can cause a heart attack and death. CPVT is caused by mutations in the RYR2 or CASQ2 genes. When a RYR2 gene mutation is involved, the condition is passed through families in an autosomal dominant fashion. When CASQ2 gene mutations are involved, the condition is inherited in an autosomal recessive fashion. In some cases the underlying cause can not be determined. Beta blockers are used to treat CPVT. An Implantable Cardioverter Defibrillator (ICD) may also be needed.
Source: GARD Last updated on 05-01-20
In medicine the word "remission" is often used to refer to a condition where there is no evidence of ongoing disease activity. The signs and symptoms of catecholaminergic polymorphic ventricular tachycardia (CPVT) are typically not constant, but serious concern is warranted for sudden CPVT events that may be triggered by activity or emotional stress. It has been estimated that 83% of people with CPVT will experience CPVT related symptoms. Symptoms of CPVT often present in childhood (75% by age 20), however CPVT has presented in older adults as well.
Last updated on 05-01-20
It has been generally recommended that young people with genetic heart disease be "cautioned against virtually all forms of vigorous physical activity." We recommend that you speak with your healthcare provider for further advice regarding your activities and restrictions.
Last updated on 05-01-20
Yes. To learn more about research studies and clinical trials involving
catecholaminergic polymorphic ventricular tachycardia, please visit the
Clinical Trials & Research tab at the following link:
http://www.rarediseases.info.nih.gov/GARD/Condition/4421/Catecholamineinduced_polymorphic_ventricular_tachycardia.aspx
Last updated on 05-01-20
While we do not have a list of doctors who specialize in treating catecholaminergic polymorphic ventricular tachycardia, we have developed the following information page titled, How To Find An Expert that has tips for finding knowledgable professionals, and may be a helpful resource.
Last updated on 05-01-20
Treatment of adults with catecholaminergic polymorphic ventricular tachycardia (CPVT) related arrhythmias typically involves the use of beta blockers. An implantable cardioverter- defibrillator (ICD) and beta blocker treatment may be considered for people with CPVT who have experienced a heart attack, fainting spells, or sustained abnormal heart rhythms on beta blockers alone. If these individuals still experience heart rhythm abnormalities flecainide and/or verapamil may also be recommended. People whose condition remains resistant to therapy may be counseled regarding further treatment options, such as left sympathetic denervation.
GeneReviews provides a current, expert-authored, peer-reviewed, full-text
articles which includes information on treatment of CPVT at the following
link:
http://www.ncbi.nlm.nih.gov/books/NBK1289/#cvt.Management
Last updated on 05-01-20
Effective treatments are available for catecholaminergic polymorphic ventricular tachycardia, however there is currently no targeted treatment that can cure CPVT at this time.
Last updated on 05-01-20
It has been recommended that all people clinically diagnosed with catecholaminergic polymorphic ventricular tachycardia (CPVT) receive treatment. Some individuals who have never had or demonstrated symptoms of CPVT, for example asymptomatic family members with CASQ2 gene mutations, may still benefit from treatment. We recommend that you speak with your healthcare provider regarding your treatment options.
Last updated on 05-01-20
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